A multiple vehicle crash near the 41-mile-marker has caused the closure of all southbound lanes, police report.

Traffic is being diverted to U.S. 31, Sgt. Stephen Wheeles with the Indiana State Police said. Wheeles is the public information officer.

The crash is near Crothersville and a semitrailer has gone over the guardrail.

There are no significant injuries, Wheeles said, and the Indiana State Police is investigating the crash.

Jackson County Sheriff’s Department and Crothersville Police Department are assisting.