A UPS truck that runs on compressed natural gas was involved in a wreck with another semitrailer late Friday night three miles south of Seymour that left Interstate 65 closed for four hours.

No one was injured in the wreck, but the compressed natural gas tank broke open, and emergency crews had to wait until it was safe before starting cleanup.

The wreck occurred at the 47-mile marker on the northbound side of the interstate, Jackson County Sheriff’s Department Deputy Jesse Hutchinson said.

Police said a UPS semi pulling double trailers and driven by Christopher French, 42, of Tennessee, was traveling northbound when it made contact with a Freightliner that was on the shoulder of the interstate. Blagojche Spasovski, 23, was the operator of the Freightliner.

The trailer being pulled by the Freightliner sustained heavy damage, Hutchinson said.

The UPS semi and its first trailer also were heavily damaged, and the truck’s second trailer flipped on its side and had to be righted, Hutchinson said.

The investigation is still ongoing, and a cause for the wreck is still being determined, Hutchinson said.

Reserve deputies Kevin Settle and Eric Browalski assisted at the scene, along with Indiana State Police, Crothersville-Vernon Township Fire Department, Jackson-Washington Township Fire Department, Indiana Department of Environmental Management, Jackson County Emergency Medical Services and 31 Wrecker.